The Structure Plus is a new top tier for Nike's stability franchise — the brand calls it its most cushioned stability shoe yet. ZoomX sits stacked on ReactX with a midfoot support system that guides the heel-to-toe transition, rather than the firm post older Structures used, at about 309 g with a 10 mm drop.
It suits you if you want modern, tall cushioning and structured support in the same shoe: the runner the Kayano and the Adrenaline serve elsewhere, staying inside the Nike wall.
It is not the lighter, cheaper Structure 26, which remains the plainer pick below it, and it is not fast — this much shoe has one speed. The support is guidance, not correction; if a clinician prescribed something specific, match the prescription, not the marketing tier.