The Kayano is ASICS' support trainer, and the 32 delivers that support through the shape of the midsole rather than a hard post. Foam in the arch firms up as you fatigue, so your foot keeps landing the same way at the end of a long run as it did at the start.
It suits runners who overpronate, and anyone whose form falls apart late in long efforts and who wants a shoe that holds it together.
It is a lot of shoe. At 300 g it is not quick and it is not trying to be - this is a shoe for easy and long miles, not for intervals. If you run neutral and want speed, the Kayano will feel like more structure than you need.